The Institute of Metabolic and Cardiovascular Diseases (I2MC) develops research to understand the pathophysiological mechanisms involved in common chronic non-communicable diseases: obesity, diabetes, thrombosis, atherosclerosis and diseases of the vessels, heart and kidney.
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EndoTreat: research project conducted in partnership with the Toulouse University Hospital (E. Chantalat), INSERM-I2MC (F. Lenfant) and the start-up company Urosphère
EndoTreat: research project conducted in partnership with the Toulouse University Hospital (E. Chantalat), INSERM-I2MC (F. Lenfant) and the start-up company Urosphère. Creating endometriosis organoids from patients’ lesions to test drug candidates. This is the challenge of the EndoTreat project led by a team from Toulouse.
We-Met plateform involved in Europen project HERVCOV:“Understand the pathogenic role of HERV-W envelope protein and develop novel prognostic markers and therapeutic targets for personalized treatment of COVID-19-associated syndromes”
Type 2 diabetes
Diabetes is a long-term excess of glucose concentration in the blood (hyperglycemia). In the case of type 2 diabetes, this is caused by a disturbance of the carbohydrate metabolism. Even if it appears gradually and insidiously, the disease has serious consequences, even fatal, in the long term.
Cardiovascular diseases (CVDs) are the leading cause of death globally, taking an estimated 17.9 million lives each year. CVDs are a group of disorders of the heart and blood vessels and include coronary heart disease, cerebrovascular disease, rheumatic heart disease and other conditions.
Kidney failure is the result of the slow evolution of the disease that leads to the destruction of the kidneys. It affects more than 82,000 people in France and requires dialysis or transplantation. In 50% of cases, chronic kidney diseases are the consequence of diabetes or high blood pressure.
Obesity is an excess of body fat and a change in adipose tissue, which can lead to health problems and shorten life expectancy. Its causes are complex. It results from the interplay of several factors – dietary, genetic, epigenetic and environmental – involved in the development and progression of this chronic disease.
Non-profit and patient associations
A.F.E.R.O is the French Association for Study and Research on Obesity. Its aim is to promote scientific exchanges, the dissemination of knowledge and training in the field of biomedical research on obesity. The AFERO can be considered as the learned society of Obesity in France.
French-speaking Society of Nephrology, Dialysis and Transplantation
The mission of the SFNDT is to support the development of nephrology in all its fields, from clinical nephrology to dialysis and renal transplantation, as well as in all dimensions of care, basic research, epidemiological and clinical advances, and education.
French Federation of Cardiology
Created in 1964, the French Federation of Cardiology is an association recognized as being of public utility since 1977. A collective vocation mobilized to reduce cardiovascular diseases.
Inserm/UPS UMR 1297 - I2MC Institut des Maladies Métaboliques et Cardiovasculaires
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