Publication d’un article de l’équipe MetaDiab (C. Moro) dans Science Advances
Carper et al. here demonstrates that reduced atrial natriuretic peptide (ANP) signaling in skeletal muscle induces prediabetes and low endurance capacity. The study shows a link between the ANP and its receptor with various metabolic traits in humans. The work may...
Publication d’un article de l’équipe MetaDiab (C. Moro) dans Cell reports
GDF15 is dispensable for the insulin-sensitizing effects of chronic exercise. Labour et al. demonstrate that the exerkine growth and differentiation factor 15 (GDF15) produced during exercise is dispensable for the insulin-sensitizing effects of chronic exercise both...
Publication d’un article de l’équipe LIPSIPLAT (PAYRASTRE / SEVERIN) dans PNAS
MTM1-mediated production of phosphatidylinositol 5-phosphate fuels the formation of podosome-like protrusions regulating myoblast fusion Myoblast fusion into multinuclear myotubes is a critical cellular process for the formation of skeletal muscle fibers. However, the...
Publication d’un article de l’équipe LYMPHACTOR (Garmy-Susini) dans Embo Molecular Medicine
Apelin-VEGF-C mRNA delivery as therapeutic for the treatment of secondary lymphedema Secondary lymphedema (LD) corresponds to a severe lymphatic dysfunction leading to the accumulation of fluid and fibrotic adipose tissue in a limb. Here, we identified apelin (APLN)...
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