Membres de l'équipe

LEZOUALCH
Frank
(DR)

LEZOUALCH Frank (DR)

frank.lezoualch@inserm.fr

0561325646

BOURGAILH-TORTOSA
Florence
(IE)

BOURGAILH-TORTOSA Florence (IE)

florence.tortosa@inserm.fr

CONTE
Caroline
(MCU)

CONTE Caroline (MCU)

caroline.conte@inserm.fr

DELMAS
Clément
(PH)

DELMAS Clément (PH)

FORMOSO
Karina
(Post-doc)

FORMOSO Karina (Post-doc)

KEHAL
Loubna
(Doc)

KEHAL Loubna (Doc)

loubna.kehal@inserm.fr

LAIREZ
Olivier
(PU-PH)

LAIREZ Olivier (PU-PH)

lairez.o@chu-toulouse.fr

MARCHEIX
Bertrand
(PU-PH)

MARCHEIX Bertrand (PU-PH)

MIALET-PEREZ
Jeanne
(CRCN)

MIALET-PEREZ Jeanne (CRCN)

jeanne.perez@inserm.fr

PANE
Roberto
(Doc)

PANE Roberto (Doc)

roberto.pane@inserm.fr

PORTERIE
Jean
(PH)

PORTERIE Jean (PH)

RESTA
Jessica
(Doc)

RESTA Jessica (Doc)

SAINTE -MARIE
Yannis
(MCU)

SAINTE -MARIE Yannis (MCU)

yannis.sainte-marie@inserm.fr

SANTIN
Yohan
(Post-doc)

SANTIN Yohan (Post-doc)

yohan.santin@inserm.fr

COUSIN
Grégoire
(Master)

COUSIN Grégoire (Master)

EYHARTS
Damien
(Master)

EYHARTS Damien (Master)

PMIDTitreAuteursAnnéeJournal
31819159Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodelingSantin Y, Fazal L, Sainte-Marie Y, Sicard P et al.2020Cell Death Differ
32589395Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac AgingIacovino LG, Manzella N, Resta J, Vanoni MA, Rotilio L, Pisani L, Edmondson DE, Parini A, Mattevi A, Mialet-Perez J, Binda C2020ACS Chem Biol.
32854274Role of EPAC1 Signalosomes in Cell Fate: Friends or Foes?Formoso K, Lezoualc h F, Mialet-Perez J.2020Cells
31974382Cardiac monoamine oxidases: at the heart of mitochondrial dysfunctionMialet-Perez J, Parini A2020Cell Death Dis.
30737259Length-independent telomere damage drives post-mitotic cardiomyocyte senescenceAnderson R, Lagnado A, Maggiorani D, et al.2019EMBO J
30873562Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stressLaudette M, Coluccia A, Sainte-Marie Y, et al.2019Cardiovascular Research
31353772Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subsetMartini H, Iacovoni JS, Maggiorani D, et al.2019Aging Cell
30003648Monoamine oxidase-A is a novel driver of stress-induced premature senescence through inhibition of parkin-mediated mitophagyManzella N, Santin Y, Maggiorani D, et al.2018Aging Cell
28096195The Multifunctional Mitochondrial Epac1 Controls Myocardial Cell DeathFazal L, Laudette M, Paula-Gomes S, Pons S, Conte C, Tortosa F, Sicard P, Sainte-Marie Y, Bisserier M, Lairez O, Lucas A, Roy J, Ghaleh B, Fauconnier J, Mialet-Perez J, Lezoualch F2017Circ Res
27344171Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transitionJansen SR, Poppinga WJ, de Jager W, Lezoualc h F, Cheng X, Wieland T, Yarwood SJ, Gosens R, Schmidt M.2016Oncotarget
26959532Oxidative Stress by Monoamine Oxidase-A Impairs Transcription Factor EB Activation and Autophagosome Clearance, Leading to Cardiomyocyte Necrosis and Heart FailureSantin Y, Sicard P, Vigneron F, Guilbeau-Frugier C, Dutaur M, Lairez O, Couderc B, Manni D, Korolchuk VI, Lezoualc h F, Parini A, Mialet-Perez J2016Antioxid Redox Signal
26941424Cyclic AMP Sensor EPAC Proteins and Their Role in Cardiovascular Function and DiseaseLezoualc h F, Fazal L, Laudette M, Conte C2016Circ Res
26370247Gadd45γ regulates cardiomyocyte death and post-myocardial infarction left ventricular remodelling.Lucas A, Mialet-Perez J, Daviaud D, Parini A, Marber MS, Sicard P2015Cardiovasc Res
25411381Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophyLaurent AC, Bisserier M, Lucas A, Tortosa F, Roumieux M, De Régibus A, Swiader A, Sainte-Marie Y, Heymes C, Vindis C, Lezoualc h F2015Cardiovasc Res
25369805Carabin protects against cardiac hypertrophy by blocking calcineurin, Ras, and Ca2+/calmodulin-dependent protein kinase II signalingBisserier M, Berthouze-Duquesnes M, Breckler M, Tortosa F, Fazal L, de Régibus A, Laurent AC, Varin A, Lucas A, Branchereau M, Marck P, Schickel JN, Deloménie C, ...,Heymes C, Lezoualc h2015Circulation