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Demonstrate 1) that intestinal microbiota and lipids are riskfactors for the control of diabetes and dyslipidemia;
2) that these risk factors regulate the enteric GLP-1 dependent gut to brain
3) that the innate and acquired immune system is a major regulator of the host to bacteria for the control of diabetes and dyslipidemia
Our partnerships are international :
Canada, Toronto , D. Drucker : Role of the inhibitors of DPPIV for the control of the action of GLP-1.
Switzerland, Lausanne: B Thorens, role of the GLUT2 glucose transporter on the control of brain GLP-1. Lausanne: Urs Scherrer: action of brain insulin, nitric oxide, and GLP1 on the control of arterial femoral blood flow.
Belgique:Bruxelles: role dietary fibers on inflammatory reaction during diabetes.
Italie, Rome: role ofTImp3 on the control of metabolic diseases.
Numerous collaborations with local reasearch teams of the institute. Numerous industrial partners, Physiogenex, Nestlé, DANISCO, MSD...
Date of update November 26, 2013